Reported in 1977-1980 among 20-39 year olds to the SurveillanceĮpidemiology and End Results Cancer Registry in the Sanįrancisco-Oakland-Standard Metropolitan Statistical Area, ![]() No cases of DUNHL and only 1 case of BL were About 0.7%-2.4% of all cases of NHL are DUNHL Non-Hodgkin's lymphoma (NHL) (4) make the precise determination of The difficulty in distinguishing DUNHL histologically fromīurkitt's lymphoma (BL) (3), a tumor often associated withĮpstein-Barr virus, and the lack of consensus on the classification Malignancy among this group of young males-i.e., DUNHL, a B-cell Report documents the possible appearance of a second unusual National Cancer Institute, National Institutes of Health Chronicĭisease Div, Center for Environmental Health, Center for Infectiousĭiseases, the Task Force on Kaposi's Sarcoma and OpportunisticĮditorial Note: Since July 1981, CDC has received reports of 162Ĭases of Kaposi's sarcoma among young homosexual males the above MD, Abraham Lincoln School of Medicine, Chicago, BJ Francis, MD,Įpidemiologist, Illinois State Dept of Public Health J Costa, MD, Svcs W McGuire, MD, University of Illinois Hospital, I Iossifides, Health, San Francisco, D Austin, MD, MPH, Dept of Health Svcs,īerkeley, J Chin, MD, State Epidemiologist, California Dept of Mary's Hospital, San Francisco, S Dritz, MD, MPH, Dept of Public Zion Hospital, San Francisco, K Yamamoto, MD, K Chick, MD, St Rosenbaum, MD, R Miner, BS, L Mintz, MD, J Gershow, MD, R Weiss, San Francisco, School of Medicine and Dentistry, L Drew, MD, E Greenspan, BDS, J Beckstead, MD, C Cassavant, PhD, D Abrams, MD, WĬhan, DDS, S Silverman, DDS, F Lozada, DDS, University of Reported by JL Ziegler, MD, G Wagner, MD, VA Medical Center, Sanįrancisco, JS Greenspan, BDS, PhD, MRC Path, EJ Shillitoe, BDS, All patients had generalized lymphadenopathy, and 3 had Or more of such infections as hepatitis B, anal warts, gonorrhea, Medical histories indicated that all 4 patients had had Included use of such drugs as nitrite inhalants, amphetamines, and ![]() Partners in common, and had no known contact with patients with They had no known contact with each other, had no known sexual Combination chemotherapy hasĪll these patients were homosexual males living in San Tumor cellsĬontained surface IgM, kappa type. On January 21, 1982, an exploratory laparotomyĭUNHL with extensive retroperitoneal involvement. Patient 4: A 24-year-old clerk developed backache and fatigue Intrathecal chemotherapy led to rapid tumor regression however, Lymphadenopathy and splenomegaly were present. Tumor was detected in the mediastinum, retroperitoneum, both Suspected abscess, but lymphadenopathy persisted. Patient 3: A 35-year-old janitor developed an enlarged Regression the patient relapsed and died in March 1982. Systemic and intrathecal chemotherapy led to temporary tumor "reactive" lymphadenopathy and mild splenomegaly were present. Retroperitoneum, the bone marrow, and the meninges. The tumor involved a left axillary lymph node, the ![]() Tumor cells contained surface IgM, kappa type, indicating aī-cell tumor. Penicillin was given for a suspectedĪbscess, but the mass enlarged. Patient 2: A 33-year-old nurse developed a tumor in his left Patient died with disseminated DUNHL on January 15, 1982. ![]() In September 1981, another tumor in the spinal cord was Radiation and chemotherapy led to complete A myelogram revealed a T4-T6 block by anĮxtradural mass. A biopsy of an orbital mass and an enlarged cervical Swelling of the right eye and an unsteady gait, and he was Shoulder pain starting in early March 1981. Patient 1: A 28-year-old hospital clerk complained of back and Potential relationship of these cases to the KSOI syndrome, they Because of the rarity of this malignancy and the Non-Hodgkins lymphoma (DUNHL) were diagnosed between March 1981 and Pathogenesis of these disorders among homosexual males in Sanįrancisco was being studied, 4 cases of diffuse, undifferentiated Immunodeficiency syndrome has been described (1,2). Homosexual males and associated with an acquired cellular Pneumonia, and other opportunistic infections (KSOI) involving Lymphoma among Homosexual Males - United StatesĪ recent outbreak of Kaposi's sarcoma, Pneumocystis carinii For assistance, please send e-mail to: Type 508 Accommodation and the title of the report in the subject line of e-mail. Persons using assistive technology might not be able to fully access information in this file.
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